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Past Events of MASSEP.org
(Complete Speaker List)
(List of All Symposium Speakers and Presentation Titles)
Thursday, April 10, Sponsored by Amgen at their Facility in Cambridge
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Speaker:
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Janusz Pawliszyn, Waterloo University, Waterloo Ontario |
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Title:
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" Bioanalytical Application of Solid Phase Microextraction Coupled to LC/MS " (Full Presentation in PDF)
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Thursday March 6, at the MIT Faculty Club, Sponsored by The Nest Group
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Speaker:
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Dr. Knut Irgum, Umea University, Umea Sweden
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Title:
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"Separation Media for HPLC from a Materials Chemistry Perspective"
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Wednesday, February 6, at the MIT Faculty Club, Sponsored by Pressure BioSciences
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Speaker:
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Dr. Steve Berkowitz, BiogenIdec, Inc.
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Title:
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"Analytical Ultracentrifugation in the Biopharmaceutical Drug Development Process"
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Wednesday, January 16, at the MIT Faculty Club, Sponsored by Agilent
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Speaker:
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Dr. Robert Weinberger, CE Technologies, Inc.
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Title:
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" The Evolution of Capillary Electrophoresis: Historical Perspective, Current Status and Future Trends"
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November29, 2007 Sponsored by Genzyme in Waltham
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Speaker:
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Dr. Richard Saferstein
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Title:
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"Forensic Science- Thirty Years of Progress".
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October 18, 2007 Sponsored by Biogen Idec in Cambridge
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Speaker:
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Thomas Chester from Procter & Gamble Company
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Title:
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"Unifying Chromatography to Meet Business Needs" (Presentation)
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9th Annual Symposium on Advances in Separation Science and Mass Spectrometry at Northeastern University Wednesday May 9, 2007
Organized by MASSEP.org and the Greater Boston Mass Spectrometry Discussion Group (GBMSDG)
Separations Speaker:
Professor Robert Kennedy (University of Michigan Department of Chemistry)(click here for speaker biography)
Title: "High-Throughput Separations" (click here for abstract)
Mass Spectrometry Speaker:
Professor Julie Leary, (University of California Davis Department of Chemistry)(click here for speaker biography)
Title: "Advancing the Frontiers of Structural Biology; Mass Spectrometry of Biological Binding Partners" (click here for abstract)
April 4, 2007 Sponsored by Dionex at the MIT Faculty Club
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Speaker:
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Prof. Frantisek Svec, University of California at Berkeley, Department of Chemistry
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Title:
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"Porous Polymer Monoliths and New Applications Thereof"
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March 6, 2007 Sponsored by Agilent at the MIT Faculty ClubMarch 6, 2007
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Speaker:
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Professor Jongyoon Han, MIT Department of Electrical Engineering and Computer Science
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Title:
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"Micro/Nanofluidic systems for proteomic sample preparation"
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January 25, 2006 Sponsored by Bruker Bioscience, Billerica, MA
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Speaker:
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Dr. Catherine Stacey, Bruker
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Title:
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"ETD - Electron Transfer Dissociation - New Approaches to Determine the Position of Post-translational Modifications in Proteins and for the Sequence Analysis of Large Peptides"
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November 15, 2006 Sponsored by Waters Corp., Milford, MA
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Speaker:
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Professor Jim Jorgenson, University of North Carolina
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Title:
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“Ultra-high Pressure Liquid Chromatography (UHPLC)“
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October 19, 2006 Sponsored by Amgen, Cambridge, MA
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Speaker:
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Michael W. Dong, Synomics Pharmaceutical Services
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Title:
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"MS-compatible HPLC Method Development for Pharmaceutics: trends, best practices and case studies"
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September 26, 2006 Sponsored by Biogen IDEC, Cambridge, MA
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Speaker:
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Dr. Brian Kelley, Wyeth Biopharma
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Title:
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"High Throughput Screening, Weak Partitioning, and a Two-Column mAb Purification Platform"
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The Eighth Symposium on
Advances in Separation Science and Mass Spectrometry,
Was at Northeastern University, Curry Student Center
Wednesday, May 10, 2006
Speakers were:
Professor Joseph Loo, UCLA
"Mass Spectrometry and Droplets: Elucidation of Protein Sequence and Complexes"
Professor Milos Novotny, Indiana University
"Combining the Strengths of Separation Science and Mass Spectrometry
in Solving Structural Problems in Glycobiology”
April 18, 2006, Hosted by Dionex at the MIT Faculty Club
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Speaker:
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C.E.C.A. Hop, Department of Pharmacokinetics, Dynamics & Metabolism, Pfizer Global Research & Development
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Title:
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" LC-MS: A Critical Tool for ADME Studies"
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March 23, 2006, Hosted by Cohesive Technologies at the MIT Faculty Club
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Speaker:
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Ralph Riggin, Director of the Commercialization Technical Center, Parenteral Manufacturing Sciences and Technology,Eli Lilly and Company
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Title:
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"Process Validation of Biopharmaceuticals"
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February 15, 2006, Hosted by Agilent at the Burlington Marriott, Burlington, MA
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Speaker:
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Joseph Zaia, Ph.D.
Center for Biological Mass Spectrometry, Dept. of Biochemistry, Boston University School of Medicine
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Title:
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"Glycomics: Glycan phenotype and disease state profiling, Applications to Connective Tissue”
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December 15, 2005, Sponsored by Genzyme, Waltham, MA
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Speaker:
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Dr. Thomas Conrads, Director of the Mass Spectrometry Laboratory in the Laboratory of Proteomics and Analytical Technologies at the National Cancer Institute in Frederick MD
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Title:
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"Identification and characterization of the antiproliferative factor: a biomarker from urine of interstitial cystitis patients"
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October 10, 2005 Sponsored by Biogen IDEC, Cambridge, MA
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Speaker:
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Professor Michael Ramsey, Minnie N. Goldby Distinguished Professor of Chemistry, University of North Carolina
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Title:
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“Micro- and Nanofluidic Devices for Chemical Separations”
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Seventh CNECC/GBMSDG Symposium, May 10, 2005
Advances in Separation Science and Mass Spectrometry,
Northeastern University, Curry Student Center, Boston, MA 02115
Jonathan Sweedler, University of Illinois, gave a lecture entitled
“Understanding neurochemistry neuron by neuron:
mass spectrometry and separations for neuroscience research”
And
Fred McLafferty, Cornell University gave a lecture entitled
“Mass Spectrometry of Biomolecules”
Abstract and Bio for Dr. Michael Dong, Thursday October 19, 2006
"MS-compatible HPLC Method Development for Pharmaceutics:
trends, best practices and case studies:"
Michael W. Dong, Synomics Pharmaceutical Services
This seminar focuses on modern trends and best practices in HPLC method development for drug substances and drug products. Several case studies will be presented to illustrate the strategies and decision process for developing HPLC methods for regulated assays and for method improvement from HPLC to Fast LC and Ultra-high-pressure LC (UHPLC).
- Review modern strategies and trends for HPLC method development
- Phase-appropriate method development and validation
- Method optimization and fine-tuning to meet ICH reporting guidelines
- Case studies: drug substances, OTC/combinational drug products and complex formulations
- Method improvements from HPLC to Fast LC and UHPLC
References:
- L.R. Snyder, J. J. Kirkland and J. L. Glajch, Practical HPLC Method Development, Wiley-Interscience, New York, 1997.
- H. Rasmussen et al, “HPLC method development”, in S. Ahuja and M.W. Dong, ed, Handbook of Pharmaceutical Analysis by HPLC, Elsevier, Amsterdam, 2005, Chapter 6
- M.W. Dong, Modern HPLC for Practicing Scientists, Wiley, 2006, Chap. 8.
Bio for Dr. M.W. Dong
Dr. Michael W. Dong is a Research Director at Synomics Pharmaceutical Services at Wareham, MA, responsible for chromatography method development/validation and conducting clients’ research projects. His research interests are Fast LC, UHPLC and methodologies for genotoxic impurities and complex formulations. Formerly, he was a Research Fellow/Group Leader at Purdue Pharma, a Senior Staff Scientist at Perkin-Elmer, and a section-head in Hoechst Celanese. He holds a B.Sc. in Chemistry from Brooklyn College and a Ph.D. in Analytical Chemistry from City University of New York. He has conducted numerous HPLC training courses at national meetings on advanced HPLC, Fast LC and HPLC method development. He pioneered Fast LC and has over 80 publications in chromatography and analytical chemistry. He authored “Modern HPLC for Practicing Scientists,” Wiley, (June) 2006 and co-edited “Handbook of Pharmaceutical Analysis by HPLC” published by Elsevier/Academic Press, 2005. He is a long-term member of Toastmasters International.
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